Taylor et al. 2021
Molecular topography of an entire nervous system
Seth R. Taylor, Gabriel Santpere, Alexis Weinreb, Marc Hammarlund, Oliver Hobert, David M. Miller
Cell,
Volume 184, Issue 16,
2021,
Pages 4329-4347.e23
Published: July 07, 2021:
Summary
- Gene expression profiles of all 118 neuron classes in the C.elegans hermaphrodite
- Each neuron type expresses a distinct code of neuropeptide genes and receptors
- Expression profiles enable discovery of cell-type-specific cis-regulatory sequences
- Cell adhesion molecules correlate with neuron-specific connectivity