Ripoll-Sánchez et al. 2023

The neuropeptidergic connectome of C. elegans

Ripoll-Sánchez L, Watteyne J, Sun H, Fernandez R, Taylor SR, Weinreb A, Bentley BL, Hammarlund M, Miller DM 3rd, Hobert O, Beets I, Vértes PE, Schafer WR.
Neuron, Volume 111, Issue 22, 2023, Pages 3570-3589.e5

Datasets

• Ripoll-Sánchez 2023 (short)
• Ripoll-Sánchez 2023 (mid)
• Ripoll-Sánchez 2023 (long)

Summary

• This paper integrates information from biochemical, gene expression and anatomical datasets to infer pathways for neuropeptide signalling between individual C.elegans neurons.

  • gene expression (Taylor et al. 2021)
  • biochemical (Beets et al. 2023)
  • anatomical datasets (White et al. 1986; Albertson & Thomson 1976; Witvliet et al. 2021)

• They generated three models (long range, mid range, short range) for neuropeptidergic connections.