Atanas et al. 2023
Brain-wide representations of behavior spanning multiple timescales and states in C. elegans
Adam A. Atanas, Jungsoo Kim, Ziyu Wang, Eric Bueno, McCoy Becker, Di Kang, Jungyeon Park, Talya S. Kramer, Flossie K. Wan, Saba Baskoylu, Ugur Dag, Elpiniki Kalogeropoulou, Matthew A. Gomes, Cassi Estrem, Netta Cohen, Vikash K. Mansinghka, and Steven W. Flavell
Cell, Volume 186, Issue 19, 2023, Pages 4134-4151.e31, ISSN 0092-8674
Published: September 14, 2023
Resources from publication
- For quantitative analysis, the two adult datasets from Witvliet et al. 2021 were averaged.
- Self looping and single synapse edges were excluded.
- For the pharyngeal circuit analysis, the connectome from the original White et al. 1986 was used as the Witvliet connectome only covers the head ganglion.
- For the 2D embedding of the connectome (the sensorimotor layer and the graph eigenvector; see below), the White et al. 1986 connectome was used to replicate the embedding previously used in the field.
2D embedding of the connectome
- The 2D embedding of connectome as performed by determining the sensorimotor layer (referred to as processing depth in the original paper) for each neuron and the 2nd eigenvector of the Laplacian of the graph. See Varshney et al. 2011 for the exact methods in determining those values.