Skip to content

Yin et al. 2024

Comparative connectomics of dauer reveals developmental plasticity

Hyunsoo Yim, Daniel T. Choe, J. Alexander Bae, Myung-kyu Choi, Hae-Mook Kang, Ken C. Q. Nguyen, Soungyub Ahn, Sang-kyu Bahn, Heeseung Yang, David H. Hall, Jinseop S. Kim & Junho Lee
Nature Communications 2024, 15:1546
Published: 27 February 2024

Datasets incorporated

Summary

  • Reconstruction of chemical connectome of the dauer, a distinct developmental stage of C. elegans
  • Uses volumetric reconstruction and automated synapse detection
  • Theoretical analysis shows a considerable rearrangement of sensory neuron connections and an increase in clustering within motor neurons during this developmental stage