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Yemini et al. 2021

NeuroPAL: A Multicolor Atlas for Whole-Brain Neuronal Identification in C. elegans

Eviatar Yemini, Albert Lin , Amin Nejatbakhsh , Erdem Varol , Ruoxi Sun, Gonzalo E Mena, Aravinthan D T Samuel, Liam Paninski, Vivek Venkatachalam, Oliver Hobert
Cell. 2021 Jan 7;184(1):272-288.e11

Summary

  • Identified brainwide expression patterns of all metabotropic receptors for ACh, GABA, and Glu completing a map of this communication network.
  • Uncovered changes in cell fate caused by TF mutations.
  • Recorded brainwide activity in response to attractive and repulsive chemosensory cues, characterizing multimodal coding for these stimuli.
  • This data was used by Ripoll-Sanchez et al. 2023 to generate the neuropeptidergic connectome.