Dataset: Wang et al. 2024 (herm.)
This dataset for the hermaphrodite C. elegans contains neurotransmitter expression values from: Wang et al. 2024 with basic anatomical connectivity information from Cook et al. 2019, and monoaminergic receptor expression information from Bentley et al. 2015
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WhiteN2U WhiteJSH White_whole Varshney Bentley2016_MA Bentley2016_PEP Cook2019Herm Cook2019Male Cook2020 Brittin2021 Witvliet1 Witvliet2 Witvliet3 Witvliet4 Witvliet5 Witvliet6 Witvliet7 Witvliet8 WormNeuroAtlas Randi2023 RipollSanchezShortRange RipollSanchezMidRange RipollSanchezLongRange Yim2024 Yim2024NonNorm Wang2024Herm Wang2024Male OpenWormUnified Test SSData UpdSSData UpdSSData2 HaspelODonovan HaspelODonovan1Seg GleesonModel OlivaresModel
Dataset taken from Wang et al. 2024. A reader combining neurotransmitter atlas values from Wang et al. 2024 (source: elife-95402-supp2-v1.xlsx) with basic anatomical connectivity information from Cook et al. 2019 Hermaphrodite connectome, and monoaminergic receptor expression information from Bentley et al. 2016. Python Reader: Wang2024HermReader
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Raw Data - Neurons - Pharynx - Social Network - Escape Response Circuit - Cook 2019 Fig 3 - BrainMap A - BrainMap B - Locomotion 1 - Locomotion 2 - Locomotion 3 - Peptidergic Hubs - Nonpharyngeal Neurons (herm) - Sensory Neurons (somatic) - Motor Neurons (somatic) - Motor Neurons and muscles - Interneurons (somatic) -
Peptidergic hubs as outlined in in Ripoll-Sánchez et al. 2023, Fig 7E
Peptidergic Hubs (PeptidergicHubs)
Peptidergic hubs as outlined in in Ripoll-Sánchez et al. 2023, Fig 7E
| Connection type | Total size | Values present | Nodes with pre connections | Nodes with post connections |
|---|---|---|---|---|
| Chemical | (4, 4) matrix | 14 non-zero entries 4 nodes with self-connections Avg. weight: 253.071429 Sum of weights: 3543.0 |
Hubs, Motor core, Periphery, Sensory core | Hubs, Motor core, Periphery, Sensory core |
| Extrasynaptic | (4, 4) matrix | 11 non-zero entries 3 nodes with self-connections Avg. weight: 177.454545 Sum of weights: 1952.0 |
Hubs, Periphery, Sensory core | Hubs, Motor core, Periphery, Sensory core |
| Acetylcholine | (4, 4) matrix | 14 non-zero entries 4 nodes with self-connections Avg. weight: 135.714286 Sum of weights: 1900.0 |
Hubs, Motor core, Periphery, Sensory core | Hubs, Motor core, Periphery, Sensory core |
| GABA | (4, 4) matrix | 11 non-zero entries 3 nodes with self-connections Avg. weight: 25.636364 Sum of weights: 282.0 |
Hubs, Periphery, Sensory core | Hubs, Motor core, Periphery, Sensory core |
| Glutamate | (4, 4) matrix | 14 non-zero entries 4 nodes with self-connections Avg. weight: 87.642857 Sum of weights: 1227.0 |
Hubs, Motor core, Periphery, Sensory core | Hubs, Motor core, Periphery, Sensory core |
| Betaine | (4, 4) matrix | 6 non-zero entries 2 nodes with self-connections Avg. weight: 22.333333 Sum of weights: 134.0 |
Periphery, Sensory core | Hubs, Periphery, Sensory core |
| Dopamine | (4, 4) matrix | 4 non-zero entries 1 nodes with self-connections Avg. weight: 294.000000 Sum of weights: 1176.0 |
Periphery | Hubs, Motor core, Periphery, Sensory core |
| Serotonin | (4, 4) matrix | 9 non-zero entries 3 nodes with self-connections Avg. weight: 54.666667 Sum of weights: 492.0 |
Hubs, Periphery, Sensory core | Hubs, Periphery, Sensory core |
| Tyramine | (4, 4) matrix | 4 non-zero entries 1 nodes with self-connections Avg. weight: 57.000000 Sum of weights: 228.0 |
Sensory core | Hubs, Motor core, Periphery, Sensory core |
| Octopamine | (4, 4) matrix | 3 non-zero entries 1 nodes with self-connections Avg. weight: 18.666667 Sum of weights: 56.0 |
Sensory core | Hubs, Periphery, Sensory core |
Weight definition: A weight of 1 indicates that the cell expresses the specific neurotransmitter, in addition to an anatomical connection between the pre- and post-synaptic cells (for Glutamate, Acetylcholine, GABA, Betaine), or (for Dopamine, Serotonin, Tyramine, Octopamine) a connection between a monoaminergic receptor-expressing cell and a monoaminergic cell according to Bentley et al. 2015.
Validation tests: See here