Dataset: Yim et al. 2024 (dauer) (non norm.)
Reconstruction of the directed chemical synaptic connectome of the dauer, a distinct developmental stage of C. elegans. Presynaptic active zones were detected by a convolutional neural network, reconstructed in 3D and proofread; postsynaptic partners and each partner's share of an active zone were assigned by simulating neurotransmitter diffusion.
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WhiteJSH WhiteN2U White_whole Varshney Bentley2016_MA Bentley2016_PEP Cook2019Herm Cook2019Male Cook2020 Brittin2021 Witvliet1 Witvliet2 Witvliet3 Witvliet4 Witvliet5 Witvliet6 Witvliet7 Witvliet8 WormNeuroAtlas Randi2023 RipollSanchezShortRange RipollSanchezMidRange RipollSanchezLongRange Yim2024 Yim2024NonNorm Yim2024Contactome Yim2024ContactomeNonNorm Wang2024Herm Wang2024Male OpenWormUnified Test SSData UpdSSData UpdSSData2 GleesonModel OlivaresModel
Dataset taken from Yim et al. 2024. Data extracted from 41467_2024_45943_MOESM6_ESM.xlsx, Yim et al. 2024 Dauer connectome (Synaptic connections; Non-normalized). Python Reader: Yim2024NonNormDataReader
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Raw Data - Neurons - Pharynx - Social Network - Escape Response Circuit - Cook 2019 Fig 3 - BrainMap A - BrainMap B - Locomotion 1 - Locomotion 2 - Locomotion 3 - Peptidergic Hubs - Nonpharyngeal Neurons (herm) - Sensory Neurons (somatic) - Motor Neurons (somatic) - Motor Neurons (head & sub lat.) - Motor Neurons and muscles - Interneurons (somatic) -
All head and sublateral hermaphrodite motor neurons
Motor Neurons (head & sub lat.) (MotorHeadSubLat)
All head and sublateral hermaphrodite motor neurons
| Connection type | Total size | Values present | Nodes with pre connections | Nodes with post connections |
|---|---|---|---|---|
| Chemical | (37, 37) matrix | 129 non-zero entries Avg. weight: 325195.117481 Sum of weights: 41950170.1550685 |
RIVL, RIVR, RMDDL, RMDDR, RMDL, RMDR, RMDVL, RMDVR, RMED, RMEL, RMER, RMEV, RMHL, RMHR, SMBDL, SMBDR, SMBVL, SMBVR, SMDDL, SMDDR, SMDVL, SMDVR, URADL, URADR, URAVL, URAVR | RIVL, RIVR, RMDDL, RMDDR, RMDL, RMDR, RMDVL, RMDVR, RMED, RMEL, RMER, RMEV, RMHL, RMHR, SIADR, SIAVL, SIAVR, SIBDL, SIBVL, SIBVR, SMBDL, SMBDR, SMBVR, SMDDL, SMDDR, SMDVL, SMDVR, URADL, URADR, URAVL, URAVR |
| Nodes in current view (37 total) xxxxxxxxxxxxxxxxxxxxxxxxx |
Num cells in node (37 total) |
Num in this dataset (34 total) |
Cells in node |
|---|---|---|---|
| RIVL | 1 | 1 | RIVL |
| RIVR | 1 | 1 | RIVR |
| RMDDL | 1 | 1 | RMDDL |
| RMDDR | 1 | 1 | RMDDR |
| RMDL | 1 | 1 | RMDL |
| RMDR | 1 | 1 | RMDR |
| RMDVL | 1 | 1 | RMDVL |
| RMDVR | 1 | 1 | RMDVR |
| RMED | 1 | 1 | RMED |
| RMEL | 1 | 1 | RMEL |
| RMER | 1 | 1 | RMER |
| RMEV | 1 | 1 | RMEV |
| RMHL | 1 | 1 | RMHL |
| RMHR | 1 | 1 | RMHR |
| SABD | 1 | 0 | SABD |
| SABVL | 1 | 0 | SABVL |
| SABVR | 1 | 0 | SABVR |
| SIADL | 1 | 1 | SIADL |
| SIADR | 1 | 1 | SIADR |
| SIAVL | 1 | 1 | SIAVL |
| SIAVR | 1 | 1 | SIAVR |
| SIBDL | 1 | 1 | SIBDL |
| SIBDR | 1 | 1 | SIBDR |
| SIBVL | 1 | 1 | SIBVL |
| SIBVR | 1 | 1 | SIBVR |
| SMBDL | 1 | 1 | SMBDL |
| SMBDR | 1 | 1 | SMBDR |
| SMBVL | 1 | 1 | SMBVL |
| SMBVR | 1 | 1 | SMBVR |
| SMDDL | 1 | 1 | SMDDL |
| SMDDR | 1 | 1 | SMDDR |
| SMDVL | 1 | 1 | SMDVL |
| SMDVR | 1 | 1 | SMDVR |
| URADL | 1 | 1 | URADL |
| URADR | 1 | 1 | URADR |
| URAVL | 1 | 1 | URAVL |
| URAVR | 1 | 1 | URAVR |
Weight definition: Weights are the summed volume (nm3) of active zone material attributed to a pre/post pair.
Validation tests: See here