Dataset: Wang et al. 2024 (herm.)
This dataset for the hermaphrodite C. elegans contains neurotransmitter expression values from: Wang et al. 2024 with basic anatomical connectivity information from Cook et al. 2019, and monoaminergic receptor expression information from Bentley et al. 2015
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WhiteN2U WhiteJSH White_whole Varshney Bentley2016_MA Bentley2016_PEP Cook2019Herm Cook2019Male Cook2020 Brittin2021 Witvliet1 Witvliet2 Witvliet3 Witvliet4 Witvliet5 Witvliet6 Witvliet7 Witvliet8 WormNeuroAtlas Randi2023 RipollSanchezShortRange RipollSanchezMidRange RipollSanchezLongRange Yim2024 Yim2024NonNorm Wang2024Herm Wang2024Male OpenWormUnified Test SSData UpdSSData UpdSSData2 HaspelODonovan HaspelODonovan1Seg GleesonModel OlivaresModel
Dataset taken from Wang et al. 2024. A reader combining neurotransmitter atlas values from Wang et al. 2024 (source: elife-95402-supp2-v1.xlsx) with basic anatomical connectivity information from Cook et al. 2019 Hermaphrodite connectome, and monoaminergic receptor expression information from Bentley et al. 2016. Python Reader: Wang2024HermReader
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Raw Data - Neurons - Pharynx - Social Network - Escape Response Circuit - Cook 2019 Fig 3 - BrainMap A - BrainMap B - Locomotion 1 - Locomotion 2 - Locomotion 3 - Peptidergic Hubs - Nonpharyngeal Neurons (herm) - Sensory Neurons (somatic) - Motor Neurons (somatic) - Motor Neurons and muscles - Interneurons (somatic) -
Subset of cells involved in locomotion
Locomotion 1 (Loco1)
Subset of cells involved in locomotion
| Connection type | Total size | Values present | Nodes with pre connections | Nodes with post connections |
|---|---|---|---|---|
| Chemical | (8, 8) matrix | 38 non-zero entries 6 nodes with self-connections Avg. weight: 9.421053 Sum of weights: 358.0 |
AVA, AVB, DA, DB, DD, VA, VB, VD | AVA, AVB, DA, DB, DD, VA, VB, VD |
| Acetylcholine | (8, 8) matrix | 30 non-zero entries 5 nodes with self-connections Avg. weight: 10.100000 Sum of weights: 303.0 |
AVA, AVB, DA, DB, VA, VB | AVA, AVB, DA, DB, DD, VA, VB, VD |
| GABA | (8, 8) matrix | 8 non-zero entries 1 nodes with self-connections Avg. weight: 6.875000 Sum of weights: 55.0 |
DD, VD | AVA, DA, DB, DD, VA, VB, VD |
| Nodes in current view (8 total) xxxxxxxxxxxxxxxxxxxxxxxxx |
Num cells in node (71 total) |
Num in this dataset (62 total) |
Cells in node |
|---|---|---|---|
| AVA | 2 | 2 | AVAL, AVAR |
| AVB | 2 | 2 | AVBL, AVBR |
| DA | 10 | 9 | DA1, DA10, DA2, DA3, DA4, DA5, DA6, DA7, DA8, DA9 |
| DB | 10 | 7 | DB1, DB10, DB2, DB3, DB4, DB5, DB6, DB7, DB8, DB9 |
| DD | 10 | 6 | DD1, DD10, DD2, DD3, DD4, DD5, DD6, DD7, DD8, DD9 |
| VA | 12 | 12 | VA1, VA10, VA11, VA12, VA2, VA3, VA4, VA5, VA6, VA7, VA8, VA9 |
| VB | 12 | 11 | VB1, VB10, VB11, VB12, VB2, VB3, VB4, VB5, VB6, VB7, VB8, VB9 |
| VD | 13 | 13 | VD1, VD10, VD11, VD12, VD13, VD2, VD3, VD4, VD5, VD6, VD7, VD8, VD9 |
Weight definition: A weight of 1 indicates that the cell expresses the specific neurotransmitter, in addition to an anatomical connection between the pre- and post-synaptic cells (for Glutamate, Acetylcholine, GABA, Betaine), or (for Dopamine, Serotonin, Tyramine, Octopamine) a connection between a monoaminergic receptor-expressing cell and a monoaminergic cell according to Bentley et al. 2015.
Validation tests: See here